Kurum Yazarı "Öztürk, Mehmet" Bitkisel Ve Hayvansal Üretim Bölümü Koleksiyonu İçin Listeleme
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Bioactivities and phenolic constituents relationship of Muğla thyme and pine honey of Turkey with the chemometric approach
Sıcak, Yusuf; Şahin Yağlıoğlu, Ayşe; Öztürk, Mehmet (Springer, 2021)The chemical ingredients of pine and thyme honey were studied, along with their medicinal activity properties. A method was validated for common honey compounds using LC-TOF/MS to analyze the ingredients. In vitro ... -
Chalcones bearing nitrogen-containing heterocyclics as multi-targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies
Sıcak, Yusuf; Kekeçmuhammed, Hüseyin; Karaküçük-İyidoğan, Ayşegül; Taşkın-Tok, Tuğba; Oruç-Emre, Emine Elçin; Öztürk, Mehmet (John Wiley and Sons Ltd, 2023)In this work, a series of chalcones (1a–d, 2a–d, 3a–d, 4a–d, and 5a–d) were designed and synthesized by Claisen–Schmidt condensation. Also, their chemical structures were elucidated using UV–Vis, FT IR, 1H NMR, 13C NMR, ... -
Design and Bioevaluation of Novel Hydrazide-Hydrazones Derived from 4-Acetyl-N-Substituted Benzenesulfonamide
Bozkurt, E; Sıcak, Yusuf; Oruç-Emre, E E; Iyidoğan, A Karaküçük; Öztürk, Mehmet (Maik Nauka/Interperiodica/Springer, 2020)In this research, a series of hydrazine-hydrazone derivatives (Ia-g), (IIa-h) were synthesized to discover new antioxidant and anticholinesterase agents. The structures of synthesized compounds were characterized by ... -
Designing heterocyclic chalcones, benzoyl/sulfonyl hydrazones: An insight into their biological activities and molecular docking study
Aktar, Bedriye Seda Kursun; Sıcak, Yusuf; Tok, Tugba Taskin; Oruc-Emre, Emine Elcin; Yaglioglu, Ayse Sahin; Iyidogan, Aysegul Karakucuk; Demirtas, Ibrahim; Öztürk, Mehmet (Elsevier, 2020)The aim of this study is to investigate the antioxidant, anticholinesterase and the antiproliferative activities of some chalcones, benzoyl and sulfonyl hydrazones. The antioxidant activity was studied by way of four ... -
Microwave-assisted synthesis of new sulfonyl hydrazones, screening of biological activities and investigation of structure-activity relationship
Karaman, Nurcan; Oruç-Emre, Emine Elçin; Sıcak, Yusuf; Çatıkkaş, Berna; Karaküçük-İyidoğan, Ayşegül; Öztürk, Mehmet (Springer Birkhauser, 2016)Sulfonyl hydrazone scaffold and the piperidine rings have important role in medicinal chemistry. This study shows the synthesis of two novel series of sulfonyl hydrazone having piperidine derivatives by condensing benzene ... -
New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors
Karaman, Nurcan; Sıcak, Yusuf; Taşkın-Tok, Tuğba; Öztürk, Mehmet; Karaküçük-İyidoğan, Ayşegül; Dikmen, Miris; Oruç-Emre, Emine Elçin (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)Hydrazones and the piperidine ring containing compounds were considered as beneficial substrates in drug design. Therefore, this study was aimed at the synthesis of new benzoyl hydrazones derived from ethyl 4-oxopiperidi ... -
Pine honey-loaded electrospun poly (vinyl alcohol)/gelatin nanofibers with antioxidant properties
Parın, Fatma Nur; Terzioğu, Pınar; Sıcak, Yusuf; Yıldırım, Kenan; Öztürk, Mehmet (Taylor & Francis Ltd, 2020)In this study, bioactive fibers were produced using polyvinyl alcohol (PVA), gelatin and pine honey by using electrospinning method. The influence of honey content (0-15 wt%) on the infrared spectrum, morphology, average ... -
Preclinical study of the medicinal plants for the treatment of malignant melanoma
Aydoğmuş Öztürk, Fatma; Jahan, Humera; Öztürk, Mehmet; Günaydın, Keriman; Choudhary, Muhammad Iqbal (Springer, 2020)Melanoma is the most aggressive type of skin cancer and originates from pigment-containing cells called melanocytes. The incidence of melanoma has been increasing worldwide. In the current study, the cytotoxic and ...