Yazar "0000-0002-1254-0683" için Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
-
Anticancer activity of linalool: comparative investigation of ultrastructural changes and apoptosis in breast cancer cells
Elbe, Hülya; Öztürk, Feral; Yiğittürk, Gürkan; Baygar, Tuba; Çavuşoğlu, Türker (TAYLOR & FRANCIS INC, 2022)Breast cancer is the most common cancer in women in the world. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Linalool is aromatic compounds from ... -
Antioxidant and anti-inflammatory potential of crocin on the doxorubicin mediated hepatotoxicity in Wistar rats
Elbe, Hülya; Demir M.; Altinöz E.; Koca O.; Önal M.O (Elsevier Ltd, 2023)Doxorubicin (DXR) is widely used in cancer treatment. However, it has not yet been possible to prevent the side effects of DXR. The aim of this study was to investigate the hepatoprotective effect of crocin against DXR ... -
Crocin treatment exerts anti-inflammatory and anti-oxidative effects in liver tissue damage of pinealectomized diabetic rats
Karayakalı, Melike; Altınöz, Eyüp; Elbe, Hülya; Koca, Oğuzhan; Önal, Melike Özgül; Biçer, Yasemin; Demir, Mehmet (Springer Science and Business Media Deutschland GmbH, 2023)Diabetes mellitus (DM) is a chronic metabolic disorder with an increasing global prevalence that leads to significant morbidity and mortality. The liver plays a vital role in glycemic regulation in physiological and ... -
Evaluation of the usage of YouTube videos about Histology and Embryology as an educational material
Çetinavcı, Dilan; Yaşar, Volkan; Yücel, Anıl; Elbe, Hülya (WILEY, 2022)The use of YouTube videos for educational purposes has been increasingly popular. The quality and accuracy of the information level of these videos should be checked by expert trainers. This study aims to evaluate the ... -
Leptin Accelerates Endothelial Wound Healing: Role of Endothelial Nitric Oxide Synthase Expression
Yiğittürk, Gürkan; Önal, Melike Özgül; Subaşı, Ekin; Doğan, Beyza; Türkmenoğlu, Melih; Kaplan, Merve; Yaşar, Volkan; Elbe, Hülya; Öztürk, Feral; 0000-0002-5315-253X (Turkish Society of Cardiology, 2022)Background: The endothelium is crucial for the control of vascular homeostasis and plays a role in angiogenesis. Leptin, a protein released mainly by adipose tissue, plays a key role in the regulation of energy balance and ... -
Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress
Altınöz, Eyüp; Öner, Zulal; Elbe, Hülya; Üremiş, Nuray; Üremiş, Muhammed (Taylor and Francis Ltd., 2021)The aim of the present study was to investigate the therapeutic and protective effects of linalool against doxorubicin (DOX)-induced kidney injury. Forty-eight Wistar rats were divided into 8 groups as follows; Control, ... -
Obesity and the Mother Goddess of Neolithic Çatalhöyük
Elbe, Hülya (Springer Science and Business Media Deutschland GmbH, 2023)Letter to Editor -
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by alpha-naphthylthiourea
Al Gburi, Mohammed Raed Abdullah; Altınöz, Eyüp; Elbe, Hülya; Yılmaz, ümit; Yılmaz, Nesibe; Karayakalı, Melike; Önal, Melike Özgül (TAYLOR & FRANCIS LTD, 2022)We aimed to observe the possible effects of melatonin (MLT) deprivation (pinealectomy) and exogenous MLT administration on pulmonary edema induced by alpha-naphthylthiourea (ANTU), a toxic chemical agent, in rats. Seventy ... -
Protective effects of quercetin against testis damage caused by cisplatin
Bostancıeri, Nuray; Taşlıdere, Aslı; Elbe, Hülya; Taşlıdere, Elif (Taylor and Francis Ltd., 2021)We investigated the effects of quercetin on cisplatin induced testicular toxicity using histopathological, immunohistochemical and biochemical methods. We used four groups of Wistar albino male: control, quercetin, cisplatin, ... -
Therapeutic role of melatonin on acrylamide-induced hepatotoxicity in pinealectomized rats: Effects on oxidative stress, NF-κB signaling pathway, and hepatocellular proliferation
Öztürk, İpek; Elbe, Hülya; Biçer, Yasemin; Karayakalı, Melike; Özgul-Önal, Melike; Altınöz, Eyüp (Elsevier Ltd, 2023)Acrylamide (AA) is formed in some foods by the cooking process at high temperatures, and it could be a carcinogen in humans and rodents. The purpose of the current study was to reveal the possible protective effects of ...