dc.contributor.author | Bakır, Buket | |
dc.contributor.author | Eliş Yıldız, Sevda | |
dc.contributor.author | Karadağ Sarı, Ebru | |
dc.contributor.author | Asker, Hasan | |
dc.contributor.author | Nazlı, Mümtaz | |
dc.date.accessioned | 2020-11-20T15:02:30Z | |
dc.date.available | 2020-11-20T15:02:30Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1300-6045 | |
dc.identifier.uri | https://doi.org/10.9775/kvfd.2015.14559 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12809/2520 | |
dc.description | WOS: 000374312100003 | en_US |
dc.description.abstract | The purpose of this study was to investigate the effects of capsaicin on the duodenal distribution of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and Transforming growth factor beta-1 (TGF beta-1) in rats. Rats were divided into two groups (n = 10 in each group). Experimental group treated with capsaicin (1 mg/kg, subcutaneously) was injected in 10% ethanol, 1% Tween and 80% distilled water everyday for a period of one week and in not injected control group. Localisations of COX-1, COX-2 and TGF beta-1 were observed in villus and crypt ephitelial cells, and smooth muscle cells. In conclusion, in this study, capsaicin administration was found to increase the release of COX-1 and COX-2, and TGF beta-1. | en_US |
dc.item-language.iso | eng | en_US |
dc.publisher | Kafkas Univ, Veteriner Fakultesi Dergisi | en_US |
dc.item-rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Capsaicin | en_US |
dc.subject | Cyclooxygenase | en_US |
dc.subject | Duodenum | en_US |
dc.subject | Transforming Growth Factor Beta-1 | en_US |
dc.title | Immunohistochemical Distribituon of COX-1, COX-2, and TGF beta-1 in the Duodenum of Rats Treated with Capsaicin | en_US |
dc.item-type | article | en_US |
dc.contributor.department | MÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Nazlı, Mümtaz | |
dc.identifier.doi | 10.9775/kvfd.2015.14559 | |
dc.identifier.volume | 22 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 333 | en_US |
dc.identifier.endpage | 338 | en_US |
dc.relation.journal | Kafkas Universitesi Veteriner Fakultesi Dergisi | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |