Music therapy can reduce both anxiety and chemotherapy-related nausea and vomiting in patients with early stage colorectal cancer treated with adjuvant infusion chemotherapy: A controlled, randomized study (PEGASUS study)

Abstract

Who initiated one of the checkpoint inhibitors. Blood samples were taken before immunotherapy treatment. Endocannabinoid (eCB) levels from various lipid families, were evaluated in a subgroup of 36 patients. Safety and effectivity of cannabis treatment in advanced cancers commencing treatment with immune checkpoint blockers was evaluated with time to tumor progression (TTP) used as a post hoc primary endpoint and overall survival (OS) and eCB concentrations as secondary endpoints with a minimum follow-up time of 7 months.